Así quedaron definidos los cuartos de final de la Liga MX:
América vs León
Rayados vs San Luis
Tigres vs Puebla
Pumas vs Chivas
TOLUCA, MEXICO - OCTOBER 27: A detail of a Liga MX sign prior the final first leg match between Toluca and Pachuca as part of the Torneo Apertura 2022 Liga MX at Nemesio Diez Stadium on October 27, 2022 in Toluca, Mexico. (Photo by Manuel Velasquez/Getty Images) 